Dr. med. Patrick Siegrist


044 387 37 11


emergency number

044 387 21 11


emergency number

044 387 37 11

Telephone switchboard at the Hirslanden Heart Center in Zurich

Dr. med. Patrick Siegrist


2023 - today

Member of the Executive Board

2019 – today

2019 - today

Heart Center Hirslanden Zurich Practice opening 01.07.2019

2016 – 2020

Senior Physician Interventional Cardiology, University Hospital Zurich function in complex PCI/coronary interventions, special CTO program

2012 – 2016

Fellowship in Invasive Cardiology University Graduated School of Medicine and Suita Tokushukai Hospital, Osaka, Japan.

Apr – Jun 2014 Visiting Invasive Cardiologist, HSC Medical Center, Kuala Lumpur, Malaysia

Apr – Sep 2016 Invasive Cardiologist Suita Tokushukai Hospital, Osaka, Japan


Heart Center Hirslanden in OA function

2003 – 2010

Residency and further training as a cardiology specialist University Hospital Zurich and Hospital Zollikerberg


Doctorate / Dissertation: Department of Nuclear Medicine, Cardiology, University Hospital Zurich "Influence of spontaneous and pacemaker-induced left bundle branch block on quantitative regional myocardial blood flow at rest and during adenosine and bicycle-induced hyperemia."


Internships in Cardiology/Hematology Mount Sinai School of Medicine, New York

1997 – 2003

Study of human medicine in Zurich

Studies & Diplomas

1984 – 1990 Primary school in Küsnacht, Switzerland

1990 – 1992 Secondary school in Küsnacht, Switzerland

1992 – 1997 Cantonal school Küsnacht (equivalent of high school and college)

Jan 1997 Matura Typus D (high school degree with modern languages)

Jan 1997 – May 1997 Military Service

Jun / Jul 1997 English course at English Language Center in Boston, MA, USA

Oct 1997 – Oct 2003 Medical school at the University of Zurich, Switzerland,

Mar / Apr 2002 Subinternship in Cardiology and Hematology, Mount Sinai School of Medicine, New York, NY, USA

Oct 2003 Graduation as MD at the University of Zurich, Switzerland

Dec 2010 Board Certification (FMH) in Cardiology, Switzerland

Oct 2011 – Dec 2011 Japanese language course at KAI Japanese School in Tokyo


Invasive cardiac examinations (coronary angiography, cardiac catheterization)

Interventional therapy of coronary artery disease (PCI with stent implantation)

Aortic valve implantation (TAVI surgeon)

Endovascular therapy of aortic aneurysm

ECG, stress ECG, long-term ECG, echocardiography

Care of adult patients with congenital heart defects


German, English, French, Spanish, Japanese


1. Tetrahydrobiopterin restores impaired coronary microvascular dysfunction in hypercholesteremia. Wyss CA, Koepfli P, Namdar M, Siegrist PT, Lüscher TF, Camici PG, P. Kaufmann PA. Eur J Nucl Med Mol Imaging 2005;32(1):84-91. Erratum in: Eur J Nucl Med Mol Imaging 2005;32(3):372

2. The quantification of absolute myocardial perfusion in humans by contrast echocardiography: algorithm and validation. Vogel R, Indermühle A, Reinhardt J, Meier P, Siegrist PT, Namdar M, Kaufmann PA, Seiler C. J Am Coll Cardiol 2005;45(5):754-62

3. Integrated PET/CT for the assessment of coronary artery disease. Namdar M, Hany TF, Koepfli P, Burger C, Wyss CA, Siegrist PT, Luscher TF, von Schulthess GK, Kaufmann PA. J Nucl Med 2005;46(6):930-5

4. Caffeine decreases exercise-induced myocardial flow reserve. Namdar M, Koepfli P, Grathwohl R, Siegrist PT, Klainguti M, Schepis T, Delaloye R, Wyss CA, Fleischmann SP, Gaemperli O, Kaufmann PA. J Am Coll Cardiol 2006;47(2):405-10

5. Repeatability of Cold Pressor Test-Induced Flow Increase Assessed with H215O and PET. Siegrist PT, Gaemperli O, Koepfli P, Schepis T, Namdar M, Valenta I, Aiello F, Fleischmann SP, Alkadhi H, Kaufmann PA. J Nucl Med 2006;47(9):1420-6

6. Assessment of myocardial perfusion by dynamic O-15-labeled water PET imaging: validation of a new fast factor analysis. Adachi I, Gaemperli O, Valenta I, Schepis T, Siegrist PT, Treyer V, Burger C, Morita K, Kaufmann PA. J Nucl Cardiol 2007;14(5):698-705

7. (13)N-ammonia myocardial perfusion imaging with a PET/CT scanner: impact on clinical decision making and cost-effectiveness. Siegrist PT, Husmann L, Knabenhans M, Gaemperli O, Valenta I, Hoefflinghaus T, Scheffel H, Stolzmann P, Alkadhi H, Kaufmann PA. Eur J Nucl Med Mol Imaging 2008;35(5):889-95

8. Diagnostic accuracy of myocardial perfusion imaging with single photon emission computed tomography and positron emission tomography: a comparison with coronary angiography. Husmann L, Wiegand M, Valenta I, Gaemperli O, Schepis T, Siegrist PT, Namdar M, Wyss CA, Alkadhi H, Kaufmann PA. Int J Cardiovasc Imaging 2008;24(5):511-8

9. Interaction of caffeine with regadenoson-induced hyperemic myocardial blood flow as measured by positron emission tomography: a randomized, double-blind, placebo-controlled crossover trial Gaemperli O, Schepis T, Koepfli P, Siegrist PT, Fleischmann S, Nguyen P, Olmsted, Wang W, Lieu H, Kaufmann PA. J Am Coll Cardiol 2008;51(3):328-9

10. Effects of AV delay programming on ventricular resynchronisation: role of radionuclide ventriculography Siegrist PT, Comte N, Holzmeister J, Sütsch G, Koepfli P, Namdar M, Duru F, Brunckhorst C, Scharf C, Kaufmann PA. Eur J Nucl Med Mol Imaging 2008;35(8):1516-22

11. Impact of hypertension on the diagnostic accuracy of coronary angiography with computed tomography. Husmann L, Scheffel H, Valenta I, Schepis T, Gaemperli O, Aepli U, Siegrist PT, Leschka S, Desbiolles L, Stolzmann P, Marincek B, Alkadhi H, Kaufmann PA. Int J Cardiovasc Imaging 2008;24(7):763-70

12. Protocol for measuring myocardial blood flow by PET/CT in cats Jenni SD, Schepis T, Jenni R, Siegrist PT, Kaufmann PA, Glaus TM. Eur J Nucl Med Mol Imaging 2008;36(2):244-9

13. Role of attenuation correction to discriminate defects caused by left bundle branch block versus coronary stenosis in single photon emission computed tomography myocardial perfusion imaging. Hoefflinghaus T, Husmann L, Valenta I, Moonen C, Gaemperli O, Schepis T, Namdar M, Koepfli P, Siegrist PT, Kaufmann PA. Clin Nucl Med 2008;33(11):748-51

14. Caffeine impairs myocardial blood flow response to physical exercise in patients with coronary artery disease as well as in age-matched controls. Namdar M, Schepis T, Koepfli P, Gaemperli O, Siegrist PT, Grathwohl R, Valenta I, Delaloye R, Klainguti M, Wyss CA, Lüscher TF, Kaufmann PA. PLoS One 2009;4(5):e5665

15. Long-term prognostic value of 13N-ammonia myocardial perfusion positron emission tomography added value of coronary flow reserve. Herzog BA, Husmann L, Valenta I, Gaemperli O, Siegrist PT, Tay FM, Burkhard N, Wyss CA, Kaufmann PA. J Am Coll Cardiol 2009;54(2):150-6

16. Left bundle branch block causes relative but not absolute septal underperfusion during exercise. Koepfli P, Wyss CA, Gaemperli O, Siegrist PT, Klainguti M, Schepis T, Namdar M, Bechir M, Hoefflinghaus T, Duru F, Kaufmann PA. Eur Heart J 2009;30(24):2993-9

17. Percutaneous closure of patent foramen ovale and valvular function – effect of the amplatzer occluder Krasniqi N, Roth J, Siegrist PT, Toggweiler S, Gruner C, Greutmann M, Tanner FC, Lüscher TF, Corti R. J Invasive Cardiol 2012;24(6):274-7

18. Outcome of percutaneous patent foramen ovale closure with the Premere occluder – a single center experience Siegrist PT, Enz T, Krasniqi N, Scherff F, Roth J, Tanner F, Corti R, Lüscher TF. J Cardiobiol 2014;2(1): 6

19. Recovery mismatch between myocardial blood flow and cardiac workload after physical exercise. Siegrist PT, Koepfli P, Namdar M, Pazhenkottil AP, Nkoulou R, Lüscher TF, Kaufmann PA. Eur Heart J Cardiovascular Imaging 2014;15(12):1386-90

20. Analysis of admission electrocardiographic patterns in survivors and non-survivors of unprotected left main acute coronary syndrome undergoing percutaneous coronary intervention. Krasniqi N, Horisberger S, Siegrist PT, Fuchs TA, Saguner AM, Scherff F, Eriksson U, Corti R, Lüscher TF. J Cardiobiol 2014;2(2): 5

21. Reproducibility and clinical potential of myocardial mass at risk calculated by a novel software utilizing cardiac computed tomography information. Sumitsuji S, Ide S, Siegrist PT, Salah Youssef, Yokoi K, Yoshida M, Awata M, Yamasaki K, Tachibana K, Kaneda H, Nanto S, Sakata Y. Cardiovasc Interv Ther. 2016;31(3):218-25

22. Right coronary artery motion analysis: a novel method to measure right ventricular systolic function by selective coronary angiography Baumann F, Obeid S, Gilhofer T, Siegrist P, von Spiczak J, Lüscher TF, Binder RK Int J Cardiovasc Imaging. 2019;35:1557-61

23. Association of the body mass index with outcomes in elderly patients (≥80 years) undergoing percutaneous coronary intervention. Leistner DM, Bazara S, Münch C, Steiner J, Erbay A, Siegrist PT, Skurk C, Lauten A. Müller-Werdan U, Landmesser U, Stähli BE. Int J Cardiol. 2019;292:73-77

24. Association of left ventricular end-diastolic pressure with mortality in patients undergoing percutaneous coronary intervention for acute coronary syndromes Leistner DM, Dietrich S, Erbay A, Steiner J, Abdelwahed Y, Siegrist PT, Schindler M, Skurk C, Haghikia A, Sinning D, Riedel M, Landmesser U, Stähli BE Catheter Cardiovasc Interv. 2020;96(4):E439-E446

25. Diagnostic performance of angiography-based quantitative flow ratio for the identification of myocardial ischemia as assessed by 13N-ammonia myocardial perfusion imaging positron emission tomography Strähl M, Schindler M, Keller LS, Holy E, Jakob P, Siegrist PT, Templin C, Maier W, Buechel RR, Kaufmann PA, Gebhard C, Stähli BE Int J Cardiol. 2020;314:13-19

26. Impact of a nationwide COVID-19 lockdown on acute coronary syndrome referrals Holy EW, Jakob P, Manka R, Stähli BE, Siegrist PT, Ruschitzka F, Templin C Cardiol J. 2020;27(5):633-635

27. Outcomes of acute coronary syndromes in coronavirus disease 2019 Cammann VL, Szawan KA, D'Ascenzo F, Gili S, Dreiding S, Würdinger M, Manka R, Stähli BE, Holy EW, Siegrist P, Jakob P, Meyer P, Iannaccone M, Di Simone E, Secco GG, Saccocci M, Bettari L, Ielasi A, Tespili M, Quadri G, Varbella F, Raposeiras-Roubin S, Abu-Assi E, Mancone M, Sardella G, Infusino F, Fedele F, Patti G, Mennuni M, Rognoni A, Bollati M, Olivotti L, Cordone S, Carugo S, Barbieri L, Gaido L, Giammaria M, Gambino A, D'Amico M, Galluzzo A, Ugo F, Trabattoni D, De Filippo O, De Ferrari GM, Vecchione C, Citro R, Ghadri JR, Templin C Clin Res Cardiol. 2020;109(12):1601-1604



Helene Frei


Medical practice assistant



Experience / Education

3-year training as medical practice assistant in the family practice of Dr. med. Thomas Frei in Meilen

1 year of professional experience in the group practice of Dr. med. Giuseppe Curcio in Tann

¾ year training as a technical surgical assistant in Zurich

Working in the practice of Dr. Siegrist since June 2021

Personal statement / motivation

I will greet you in a friendly manner on the phone and will be happy to coordinate your appointment requests. I take time for your concerns and can help with your questions. During your examination in our practice, it is important to me that you feel comfortable and taken seriously. Therefore, you are welcome to visit us as a patient.


German, English, French


T 044 387 37 11
F 044 387 22 40